The dry powder needle is to quickly freeze the sterile solution of the medicine to about 40 degrees Celsius, and then slowly heat under vacuum to make the water of the solution sublimate while maintaining the frozen powder injection. The common production process is as follows: firstly, the medicine is made into a liquid medicine according to the standard of water injection, and the impurities and bacteria are removed by filtration and ultrafiltration in a state of 100, and the bottle is semi-plugged aseptically, and is quickly frozen in a freeze dryer. When the temperature is below 40 degrees, the liquid is solid. In this state, the ultimate vacuum (<0.009Pa) is used to sublimate the water, and the drug is crystallized and dried into a bulky crystal. After the sublimation is completed, it is automatically stoppered under vacuum. Crystallized freeze-dried powder needles with bacteria, vacuum and water content <0.01% were produced. Therefore, the general freeze-dried powder needle on storage does not need to be refrigerated, and can be stored at room temperature.

The freeze-dried powder needle has good stability compared with the general powder needle and water injection: because the freeze-dried powder needle is made and stored under vacuum, the vacuum state is almost no oxygen, the medicine will not be oxidized; the water content of the freeze-dried powder needle Very low (<0.01%), will not be hydrolyzed; freeze-dried powder needle production process is strictly sterile (up to 100 standards), will not be contaminated, so freeze-dried powder needle stability. The freeze-dried powder needle also has a faster effect than the general powder needle and has high bioavailability. This is because the special production process of freeze-dried powder needles allows the drug to be evenly dispersed in the ice shelf formed by lyophilization such as chitosan. This structure enlarges the surface area of ​​the drug, so that the drug can contact more germs per unit time. Thereby having a quick function. The special ice shelf structure formed by chitosan allows the drug to exist in the nanocapsules in a single microcapsule, which is released as the blood circulation reaches the lesion site, which improves the bioavailability of the drug.

The high-tech of freeze-dried powder needles is as follows: freeze-dried powder needles are vacuum-free, sterile, extremely low in water content, quick-freezing in the production process, high-tech content such as sublimation, and the following high-tech content:

(1) Microencapsulation or formation of liposomes: by screening lyophilized carriers, adjusting the shape of ice shelves and the size of micropores, the drugs can be microencapsulated or formed into liposomes by screening different microcapsules and lipids. The plastids allow the drug to achieve rapid, targeted or controlled release.

(2) By adjusting the carrier and freeze-drying process, the two drugs can be combined into a double salt under specific environmental conditions, the latter can make the two drugs reach the lesion at the same time, play a synergistic effect, and greatly improve the bactericidal efficacy of the antibacterial drug. . And the double salt enhances the stability of the drug.

The reason why the drug is made into a freeze-dried powder is:

(1) Some drugs have poor stability, or see water is easy to decompose, can not be made into ordinary powder needles or water needles, only the lyophilized powder needle can play a good role.

(2) Some drugs are stable in one species, and are easy to react with another drug. It can not be preserved for a long time as an ordinary injection. The compatibility of the two drugs is very effective in clinical practice, and the lyophilized powder can be used to solve the compatibility. A problem that is not easy to exist for a long time.

(3) The microencapsulation or formation of liposomes, complexation into complex salts, etc., so that the drug can play a quick and effective role, improve the bioavailability of the drug. A targeted or controlled release agent can also be prepared by adjusting the carrier.

The lyophilized powder needle is generally used as a diluent for water for injection or 5% glucose, and a special diluent is used for individual varieties. It is generally not recommended to dilute with saline or with a partial water injection. Generally speaking, the appropriate diluent should be selected according to the instructions, and should be used up as soon as possible after dilution. The unused liquid has poor stability and can be reused according to the instructions. General medicine can be stored for 1-3 days at room temperature, 3-7 days for cold storage (2-8C), and one month for freezing (-10C). Expired should be discarded.

The freeze-dried powder needle should be used in combination with other water needles depending on the specific conditions. The freeze-dried powder needle can be used in combination with some water injections. For details, refer to the drug compatibility contraindication table promulgated by the State General Administration of Medicine.

Freeze-dried powder medicine has cracks or fragments in the bottle, which does not affect the efficacy. Please feel free to use it. Because the moisture content of the freeze-dried powder needle is extremely low, cracks will appear in the freeze-drying process, just like the ground crack and the crack does not affect the efficacy. The freeze-dried powder needle is made under vacuum, the drug is agglomerated and the transport process may be broken, and the effect is not affected at all. Please feel free to use it. Note that: freeze-dried powder needles are stable before dilution, the agent can not be preserved for a long time, and the two drugs are compatible, and the clinical effect is very good. The lyophilized powder can solve the problem that the compatibility is not easy to exist for a long time.

NPT Thread Brass P.T.C Fittings

In the beginning of 2015, Cixi Air-Fluid Brass Nickel-Plated Push to Connect Fittings passed 90,000 impulse test @ 500 bar working pressure in U.S.A Customers' Labotory.


Cixi Air-Fluid Brass Nickel-Plated Push To Connect Fittings passed the Quality tested by "National Quality Supervision and Inspection Center of Pneumatic Products" .



All the Cixi Air-Fluid NPT Tapered Threads with a groove on Hexagon body to easily distinguish it from the BSPT Tapered Threads Fittings.


The Cixi Air-Fluid fittings' come into configurations as below:

a.Brass Straight MNPT Male Push to Connect Fittings
b.Brass Straight Female NPT Push to Connect Fittings
c.90 Degree Elbow Brass Push to Connect Air Hose Fittings
d.Nickel-Plated Brass Branch Tee Push to Connect Fittings
e.Nickel-Plated Brass Run Tee Push to Connect Fittings
f.Brass N.P Bulkhead Female NPT Thread Fittings

Air-Fluid NPT Thread Branch Tee Fittings









NPT Thread Brass P.T.C Fittings, PTC Air Fittings, NPT Brass Fittings, NPT Thread Fittings

Ningbo Air-Fluid Pneumatic Components Co., Ltd , https://www.air-fittings.com