Smartphones have become an indispensable part of our lives. Many scientists are also trying to develop mobile applications to diagnose and monitor diseases. Diabetes is probably one of the most widely used diseases.

中国科学家发明光控细胞:用手机可操纵治疗糖尿病

Cover of Science Translational Medicine

This time, researcher Ye Haifeng from East China Normal University led his team to publish a cover article in the journal Science Translational Medicine. They combined their smartphones with optogenetics to remotely use mobile apps and special LED lights. Regulate the treatment of diabetes!

So how is this done? To sum up briefly, first we need a Bluetooth-enabled blood glucose meter that can transfer blood glucose data to the mobile app. The app processes the data to determine the blood sugar level. When the app determines that the blood sugar level is too high, it triggers the implant. Into the mouse, an LED lamp that emits far-infrared light. The light-irradiated cells can secrete insulin or glucagon-like peptide-1 (GLP-1, a peptide secreted by the ileum, which can reduce bowel movements, inhibit gastric emptying, help control diet, and reduce body weight. As a target for the action of type 2 diabetes drugs, the blood sugar of mice can be reduced to the normal range!

中国科学家发明光控细胞:用手机可操纵治疗糖尿病

Ye Haifeng Researcher (front row, right) and his team

Researcher Ye Haifeng graduated from East China Normal University in 2007 and received his Ph.D. from the Federal Institute of Technology in Zurich, Switzerland in 2012. In 2014, he was selected as the eleventh national “Thousand Talents Program” youth project, and returned to his alma mater, East China Normal University. . Dr. Ye specializes in the field of synthetic biology, using synthetic biology concepts, artificially designing and synthesizing intelligent gene network control systems, and for the diagnosis and treatment of diseases.

For this new study, Dr. Ye believes that this is an important step toward the era of personalized and digital precision medicine. Although the previous introduction sounds simple, there seems to be no "difficulty", but exploring this "ingenious system" is really not that easy.

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